ACC.26丨搶鮮探秘：27項LBCT研究提前看！

POCKETIN

New Orleans

一起探索心血管醫學的未來

北京時間3月28日至30日，由美國心臟病學會（ACC）舉辦的心血管領域盛會——ACC.26學術會議將在美國新奧爾良隆重舉行。本次為期3天的會議亮點滿滿，設有7場最新突破性臨床試驗（Late-Breaking Clinical Trials），將公布27項前沿臨床研究成果。其中，來自中國南京市第一醫院的陳紹良教授將在壓軸的LBCT VII專場報告其團隊的重要研究，展現中國學者在國際頂尖學術舞臺上的影響力。

POCKETIN基于各大研究注冊信息及既往公布的相關研究文獻，推出“LBCT 搶先看”欄目，請您緊跟我們的步伐，一同踏上這場充滿驚喜與挑戰的ACC.26學術之旅。

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重磅研究，先睹為快

LBCT 搶先看

7場LBCT專場

27項最新研究

跟隨我們

提前探秘ACC.26

解鎖心臟醫學新進展

02

LBCT日程一覽

Late-Breaking Clinical Trials I

北京時間：3月28日 23:30-00:30

Ultrasound-Facilitated Catheter-Directed Thrombolysis Vs Anticoagulation Alone For Acute Intermediate-High-Risk Pulmonary Embolism: Primary Results of the HI-PEITHO Randomized Clinical Trial
急性中高危肺栓塞超聲輔助導管導向溶栓 vs. 單純抗凝治療：HI-PEITHO隨機臨床試驗主要結果
Stavros V. Konstantinides
Outcomes in Patients With Atrial Fibrillation Randomized to Receive Left Atrial Appendage Closure or Oral Anticoagulation: Primary Results of the CHAMPION-AF Clinical Trial
隨機接受左心耳封堵術或口服抗凝治療的房顫患者的結局：CHAMPION-AF臨床試驗的主要結果
Saibal Kar Primary Left Ventricular Unloading in Anterior ST-Segment Elevation Myocardial Infarction (STEMI) Without Cardiogenic Shock: Results From the STEMI-Door to Unload Randomized Clinical Trial
無心源性休克前壁ST段抬高型心肌梗死的早期左心室減負荷治療：STEMI-Door to Unload隨機臨床試驗結果
Navin Kapur

Late-Breaking Clinical Trials II

北京時間：3月29日 5:45-6:45

Kardinal: A Phase 2 Study of Tonlamarsen For the Treatment of Uncontrolled Hypertension
KARDINAL研究：評估Tonlamarsen治療未控制高血壓的2期臨床試驗

Luke Laffin

Evolocumab in Patients Without Significant Atherosclerosis: Results From VESALIUS-CV
依洛尤單抗在無顯著動脈粥樣硬化患者中的應用：VESALIUS-CV研究結果
Nicholas Marston Intensive Low-Density Lipoprotein Cholesterol Targeting in Patients With Atherosclerotic Cardiovascular Disease
動脈粥樣硬化性心血管疾病患者強化低密度脂蛋白膽固醇目標值設定
Yong-Joon Lee
DASH-Patterned Groceries to Reduce Blood Pressure Among Adults With Treated Hypertension: Results From the GoFreshRx Randomized Clinical Trial
為經治療的高血壓成人提供DASH模式食品以降低血壓：GoFreshRx隨機臨床試驗結果

Stephen Paul Juraschek

Late-Breaking Clinical Trials III

北京時間：3月29日 22:30-23:30

Controlled Trial of High-Risk Coronary Intervention With Percutaneous Left Ventricular Unloading (CHIP-BCIS3)
高危冠狀動脈介入治療中經皮左心室減負荷技術的對照試驗：CHIP-BCIS3研究
Divaka Perera
A Large-Scale, Global Randomized Trial of Coronary Physiology Derived From Conventional Angiography Compared With An Invasive Pressure Wire-Based Approach to Guide Percutaneous Coronary Intervention
一項大規模全球隨機試驗：比較基于常規造影衍生的冠狀動脈生理學與基于有創壓力導絲的方法指導經皮冠狀動脈介入治療
Ajay J. Kirtane A Randomized, Placebo-Controlled Trial of Chronic Total Occlusion Percutaneous Coronary Intervention in Stable Angina- ORBITA-CTO Trial
穩定型心絞痛患者慢性完全閉塞病變經皮冠狀動脈介入治療的隨機、安慰劑對照試驗——ORBITA-CTO試驗
Sarosh A. Khan
Fractional Flow Reserve or 3d-quantitative Coronary Angiography-Based Vessel-Ffr Guided Revascularization – The Fast Iii Trial
血流儲備分數或基于3D定量冠狀動脈造影的血管FFR指導血運重建——Fast III試驗

Joost Daemen

Late-Breaking Clinical Trials IV

北京時間：3月30日 00:45-1:45

Spironolactone in the Treatment of Heart Failure
螺內酯治療心力衰竭
Frank Edelmann
Efficacy and Safety of Sotatercept in Combined Post- and Pre-Capillary Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction: Results From the Phase 2 Cadence Trial
Sotatercept在射血分數保留型心力衰竭相關的毛細血管前后混合性肺動脈高壓中的療效與安全性：2期Cadence試驗結果

Mardi Gomberg-Maitland

Lung Impedance-Guided Therapy in Heart Failure With Preserved Ejection Fraction: Results of a Randomized Clinical Trial
基于肺阻抗監測指導射血分數保留型心力衰竭治療：一項隨機臨床試驗結果
Michael Kleiner Shochat
Mavacamten in Symptomatic Adolescent Patients With Obstructive Hypertrophic Cardiomyopathy: Results From the Phase 3 Scout-HCM Trial
Mavacamten用于有癥狀的青少年梗阻性肥厚型心肌病患者：來自3期Scout-HCM試驗的結果
Joseph William Rossano

Late-Breaking Clinical Trials V

北京時間：3月30日 6:00-7:00

Redo-Surgery Versus Transcatheter Valve-In-Valve For Mitral Bioprosthetic Dysfunction: The SURVIV Trial
再次外科手術 vs. 經導管瓣中瓣技術治療二尖瓣生物瓣功能障礙：SURVIV試驗

Dimytri Siqueira

Transcatheter Aortic Valve Implantation Without Routine Percutaneous Coronary Intervention: A Randomized Controlled Trial

不常規進行經皮冠狀動脈介入治療的經導管主動脈瓣植入術：一項隨機對照試驗

Michiel Voskuil

Protect The Head To Head Trial: Randomized Comparison of Emboliner Embolic Protection Catheter Vs. Sentinel Cerebral Protection System During Transcatheter Aortic Valve Replacement
Protect The Head to Head試驗：Emboliner栓塞保護導管與Sentinel腦保護系統在經導管主動脈瓣置換術中的隨機對比研究
Adam B. Greenbaum
Two-Year Outcomes After Transcatheter Tricuspid Repair Without Cross-over in the Randomized Tri-fr Trial
Tri-Fr隨機試驗中無交叉治療的經導管三尖瓣修復術后兩年結局
Erwan Donal

Late-Breaking Clinical Trials VI

北京時間：3月30日 22:30-23:30

Effects Of A Food-is-medicine Intervention On Blood Pressure Among Black And Hispanic Adults With Hypertension In Healthy Food Priority Areas: The Thrive Pilot Trial
“食物即藥物”干預對健康食品優先區域中患有高血壓的黑人和西班牙裔成年人血壓的影響：Thrive 初步試驗
Oluwabunmi Ogungbe
Digoxin in Rheumatic Heart Disease: A Multi-Center, Randomized, Double Blind, Placebo-controlled Trial
地高辛用于風濕性心臟�。阂豁椂嘀行�、隨機、雙盲、安慰劑對照試驗
Ganesan Karthikeyan Discontinuation of β-blocker Therapy in Stabilized Patients After Acute Myocardial Infarction
急性心肌梗死后病情穩定患者停用β受體阻滯劑治療
Joo-Yong Hahn
Effect of Intensive Triglyceride Lowering With Olezarsen on Progression of Coronary Atherosclerosis: A Coronary Cta Substudy of The Essence-TIMI 73b Randomized Trial
Olezarsen強化降低甘油三酯對冠狀動脈粥樣硬化進展的影響：Essence-TIMI 73b隨機試驗的冠狀動脈CTA亞組研究
Nicholas Marston

Late-Breaking Clinical Trials VII

北京時間：3月31日 00:45-1:45

Primary Efficacy and Safety Results From the Phase 3 Sirolimus-Coated Balloon For Infra-inguinal Peripheral Arterial Disease (SirPAD) Trial
西羅莫司涂層球囊治療腹股溝下外周動脈疾病的3期SirPAD試驗主要療效與安全性結果
Stefano Barco
Intravascular Ultrasound Guidance For Complex High-Risk Indicated Procedures – The Ivus Chip Trial
血管內超聲指導復雜高危有指征手術——Ivus Chip試驗

Roberto Diletti

Intravascular Ultrasound-Guided Versus Angiography-Guided Percutaneous Coronary Intervention In Unprotected Left Main Coronary Artery Disease – The Optimal Trial
血管內超聲引導對比造影引導的經皮冠狀動脈介入治療在無保護左主干冠狀動脈疾病中的應用——Optimal試驗
Adrian Banning
Ivus Or Angiography Guidance For PCI in Complex Coronary Bifurcation Lesions
復雜冠狀動脈分叉病變PCI術中血管內超聲或血管造影指導

南京市第一醫院 陳紹良

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