*僅供醫(yī)學(xué)專業(yè)人士閱讀參考

埃萬(wàn)妥單抗聯(lián)合蘭澤替尼方案正式獲得NMPA批準(zhǔn)，成為中國(guó)EGFR敏感突變晚期非小細(xì)胞肺癌一線治療新增選擇。

*以下內(nèi)容僅供醫(yī)療衛(wèi)生專業(yè)人士瀏覽。

參考文獻(xiàn)：

[1]Cho BC, Lu S, Felip E, et al. Amivantamab plus Lazertinib in Previously Untreated EGFR-Mutated Advanced NSCLC. N Engl J Med. 2024;391(16):1486-1498.

[2]Lu S, Byoung CC, Jong-Seok L, et al. Amivantamab Plus Lazertinib vs Osimertinib as First-line Treatment Among Asian Patients With EGFR-mutated, Advanced Non-small Cell Lung Cancer (NSCLC): MARIPOSA Subgroup Analysis. 2023 ESMO Aisa. LBA10.

[3]Cho BC, Lu S, Felip E, et al. Amivantamab plus lazertinib vs osimertinib in first-line (1L) EGFR-mutant (EGFRm) advanced NSCLC: Final overall survival (OS) from the phase III MARIPOSA study. 2025 ELCC. 4O.

[4]NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines?) Non-Small cell LungCancer Version 7.2025.

[5]中國(guó)臨床腫瘤學(xué)會(huì)（CSCO）非小細(xì)胞肺癌（NSCLC）診療指南（2025年）

[6]Cho BC, Lu S, Felip E, et al. Amivantamab plus Lazertinib in Previously Untreated EGFR-Mutated Advanced NSCLC. N Engl J Med. 2024;391(16):1486-1498.

[7]Spira AI, Paz-Ares L, Han JY, et al. Preventing Infusion-Related Reactions With Intravenous Amivantamab-Results From SKIPPirr,a Phase 2 Study:A Brief Report.J Thorac Oncol. Published online January 24,2025.

[8]Nicolas G, Li WM, Alexander lS, et al.Preventing moderate to severe dermatologic adverse events in first-line EGFR-mutant advanced NSCLC treated with amivantamab plus lazertinib:Early success of the COCOON trial.2025 ELCC. 10MO.

[9]Feldman JL, Cho BC, Li W, et al. Dermatologic prophylaxis and impact on patient-reported outcomes in first-line EGFR-mutant advanced NSCLC treated with amivantamab plus lazertinib: Results from the phase 2 COCOON trial. 2025 ASCO. Abstract 8641.

審批編號(hào)：CP-551633 審批時(shí)間：11/11/2025 過(guò)期時(shí)間：11/11/2026

*此文僅用于向醫(yī)療衛(wèi)生專業(yè)人士提供科學(xué)信息，不代表平臺(tái)立場(chǎng)。